{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/0185cea5-9e3b-4b82-a887-26f91f92765f/63f8d83bcef8ec001115c2a3?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Audio long read: How your first brush with COVID warps your immunity","thumbnail_width":200,"thumbnail_height":200,"thumbnail_url":"https://open-images.acast.com/shows/61b9f3b71a8cbe675f3cedcb/show-cover.jpg?height=200","description":"<p>Imprinting is a quirk of the immune system in which someone’s initial exposure to a virus biases their immune response when they meet the same virus again.</p><p><br></p><p>Studies are showing how imprinting shapes people’s responses to SARS-CoV-2; those infected with earlier strains can mount weaker responses to a later Omicron infection.</p><p><br></p><p>This phenomenon is dampening the hope that variant-tailored boosters will markedly reduce transmission of the virus, although researchers agree that variant-tailored boosters are worth getting because they still provide some immunity, and prevent serious illness.</p><p><br></p><p>This is an audio version of our Feature: <a href=\"https://www.nature.com/articles/d41586-023-00086-1\" rel=\"noopener noreferrer\" target=\"_blank\">How your first brush with COVID warps your immunity</a></p><p><br></p>","author_name":"Springer Nature Limited"}