{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/0185cea5-9e3b-4b82-a887-26f91f92765f/5ebcb152-67d9-4e97-8554-901a5c41ea46?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Nature PastCast, August 1975: Antibodies’ ascendency to blockbuster drug status","thumbnail_width":200,"thumbnail_height":200,"thumbnail_url":"https://open-images.acast.com/shows/61b9f3b71a8cbe675f3cedcb/61b9f40a77010000158181ba.jpg?height=200","description":"<p>This year, <em>Nature</em> celebrates its 150th birthday. To mark this anniversary we’re rebroadcasting episodes from our <em>PastCast</em> series, highlighting key moments in the history of science.</p><p><br></p><p>They’re found in home-testing kits for pregnancy, hospital tests for MRSA, and in six out of ten of the best-selling drugs today. But monoclonal antibodies have kept a surprisingly low profile since their debut in a <em>Nature</em> paper in 1975. This podcast follows them from that time through patent wars, promising drug trials and finally to blockbuster status today.</p><p><br></p><p><em>This episode was first broadcast in August 2013.</em></p><p><br></p><p><strong>From the archive:</strong></p><p><br></p><p><a href=\"https://www.nature.com/articles/256495a0\" target=\"_blank\">Continuous cultures of fused cells secreting antibody of predefined specificity</a>, by Köhler &amp; Milstein</p><p><br></p><p><em>Margaret Thatcher speech clips courtesy of the </em><a href=\"https://www.margaretthatcher.org/\" target=\"_blank\"><em>Margaret Thatcher Foundation</em></a><em>. </em></p>","author_name":"Springer Nature Limited"}